COVID-19 a Serious Health Issue - A Literature Review of Various Journal around the World

Devesh Joshi, Rashi Bahuguna

Abstract: COVID-19 is an infectious disease which is caused nCoV belongs to the -coronavirus genus. It is proposed that the major host for alphacoronaviruses and betacoronaviruses are Bats Its transmitted from infected person who has symptoms from virus including cough and sneezing, to susceptible person via airborne, zoonotic droplet nuclei. Due to the absence of specific Vaccine and Antiviral drug Epidemilogical reports suggest that the morbidity and mortality rate is drastically increases day by day. The common clinical symptoms include fever, sore throat, cough, myalgia, headache, fatigue, headache, and breathlessness or dyspnea. Infection is confirmed by positive test to SARS-CoV-2 by real-time RT-PCR, In India it is done in National Institue of Virology in Pune. Some drugs shows invitro efficacy against Novel Coronavirus (2019-nCoV) i. e. chloroquine and hydroxychloroquine (Antimalarial Drugs), Liponavir and Ritonavir (HIV protease inhibitor). Supportive therapy include Azithromycin, Tocilizumab, some Immunomodulators and NSAIDs. Some safety measure should also be taken like wash your hands with soap, use senitizers, cover your mouth with elbow during cough or sneeze.

Keywords: nCoV, COVID-19, coronavirus, SARS-CoV-2, RT-PCR, 2019-nCoV, HIV, ARDS, respiratory syndrome, infectious disease